Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325793 | 0.86 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4ETMEM97SIGMAR1 | |
| SCHEMBL3570124 | 0.81 | LMNA (0.65) | ALDH1A1MAPTLMNAKDM4EUSP2 | |
| Hydrochloric Acid SCHEMBL9053101 | 0.79 | LMNA (0.66) | ALDH1A1MAPTLMNAKDM4EUSP2 | |
| SCHEMBL7037787 | 0.78 | LMNA (0.62) | ALDH1A1MAPTLMNAKDM4EUSP2 | |
| SCHEMBL9324328 | 0.77 | TMEM97 (0.48) | ALDH1A1MAPTLMNAKDM4EUSP2 | |
| SCHEMBL4337942 | 0.75 | MAPT (0.55) | ALDH1A1MAPTLMNAKDM4EUSP2 | |
| SCHEMBL7915502 | 0.75 | TMEM97 (0.60) | ALDH1A1MAPTLMNAKDM4EUSP2 | |
| SCHEMBL9827447 | 0.74 | RAB9A (0.60) | ALDH1A1MAPTLMNAKDM4EUSP2 | |
| SCHEMBL7916132 | 0.74 | PRMT5 (0.64) | ALDH1A1MAPTLMNAKDM4EUSP2 | |
| SCHEMBL10897096 | 0.73 | TMEM97 (0.54) | ALDH1A1MAPTLMNAKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310941-A | Antiarrythmia agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-05-10 | — | — | US | disclosed |
| US-5208252-A | Antiarrhythmia | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |