Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321412 | 0.86 | SMN1; SMN2 (0.48) | KMT2AALDH1A1MEN1 | |
| SCHEMBL9321415 | 0.82 | SIGMAR1 (0.48) | LTA4HKMT2ASLC6A3MEN1 | |
| SCHEMBL9322137 | 0.81 | SIGMAR1 (0.47) | LTA4HKMT2AMEN1 | |
| SCHEMBL9322205 | 0.81 | SIGMAR1 (0.47) | LTA4HKMT2AMEN1 | |
| SCHEMBL9322356 | 0.80 | BCHE (0.47) | LTA4HKMT2AALDH1A1 | |
| SCHEMBL9323712 | 0.79 | SMN1; SMN2 (0.50) | GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL9322164 | 0.75 | DPP7 (0.49) | KMT2ASLC6A3MEN1 | |
| SCHEMBL9323630 | 0.74 | DPP7 (0.48) | KMT2ASLC6A3MEN1 | |
| SCHEMBL10540040 | 0.74 | CCR3 (0.51) | KMT2AALDH1A1MEN1 | |
| SCHEMBL5365328 | 0.73 | ALDH1A1 (0.64) | GAALTA4HKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |