Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322356 | 0.94 | BCHE (0.47) | SMN1; SMN2TP53ALDH1A1BCHEGNAI3 | |
| SCHEMBL9323712 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1GNAI3GNAO1GNAI1 | |
| SCHEMBL9324616 | 0.86 | GAA (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9322401 | 0.86 | GAA (0.40) | SMN1; SMN2TP53ALDH1A1GNAI3GNAO1 | |
| SCHEMBL9323677 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2TP53GNAI3GNAO1GNAI1 | |
| SCHEMBL9324758 | 0.82 | LTA4H (0.42) | SMN1; SMN2TP53ALDH1A1BCHEHSD17B10 | |
| SCHEMBL9323550 | 0.82 | TP53 (0.39) | SMN1; SMN2TP53FPR3FPR2 | |
| SCHEMBL9322225 | 0.81 | THRA (0.40) | SMN1; SMN2TP53ALDH1A1BCHEGNAI3 | |
| SCHEMBL3937676 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53ALDH1A1BCHELMNA | |
| SCHEMBL9322261 | 0.78 | HRH3 (0.36) | SMN1; SMN2TP53HRH3FPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |