Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260235 | 0.90 | PDE4D (0.43) | FPR2PDE4DSMN1; SMN2PDE4APDE4B | |
| SCHEMBL9268068 | 0.85 | ALDH1A1 (0.43) | PDE4DSMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL9265363 | 0.85 | PDE4D (0.43) | PDE4DSMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL9325535 | 0.85 | FPR2 (0.47) | FPR2PDE4BMAPTALDH1A1MEN1 | |
| SCHEMBL9263149 | 0.84 | PDE4D (0.39) | PDE4DSMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL9264413 | 0.83 | SMN1; SMN2 (0.57) | PDE4DSMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL9271875 | 0.82 | PDE4D (0.44) | PDE4DSMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL9268561 | 0.82 | TRPC6 (0.46) | FPR2SMN1; SMN2LMNATP53MAPT | |
| SCHEMBL9267064 | 0.81 | PDE4D (0.53) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9616213 | 0.81 | FPR2 (0.41) | FPR2PDE4DSMN1; SMN2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581805-A1 | NOVEL PYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992019602-A1 | NOVEL PYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-11-12 | — | — | WO | disclosed |