SCHEMBL932900

SCHEMBL932900

CC(C)(c1ccc(NCC2CO2)cc1)c1ccc(NCC2CO2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.51
TSHR P16473 3/20 0.51
MAPT P10636 3/20 0.51
ALDH1A1 P00352 3/20 0.51
TP53 P04637 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CYP1A2 P05177 1/20 0.51
PPARG P37231 1/20 0.51
HIF1A Q16665 1/20 0.51
NR3C2 P08235 2/20 0.36
PTPN11 Q06124 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ESR1 P03372 1/20 0.33
CYP3A4 P08684 1/20 0.33
AR P10275 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16641019 1.00 HPGD (0.51) HPGDTSHRMAPTALDH1A1TP53
SCHEMBL8981580 0.84 SMN1; SMN2 (0.42) TSHRMAPTALDH1A1TP53HIF1A
SCHEMBL13384519 0.84 ALDH1A1 (0.70) HPGDTSHRMAPTALDH1A1TP53
SCHEMBL244947 0.79 MAPT (0.50) HPGDMAPTALDH1A1TP53MEN1
SCHEMBL21401818 0.79 SMN1; SMN2 (0.39) TSHRMAPTALDH1A1TP53HIF1A
SCHEMBL20057512 0.78 MAPT (0.44) HPGDTSHRMAPTALDH1A1TP53
SCHEMBL9685247 0.76 NPC1 (0.37) ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL4271408 0.76 L3MBTL1 (0.41) HPGDMAPTALDH1A1MEN1KMT2A
SCHEMBL7535852 0.76 LMNA (0.38) HPGDALDH1A1MEN1KMT2ANPC1
SCHEMBL11702489 0.76 RAB9A (0.37) HPGDMAPTALDH1A1TP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000040634-A2 MODIFIED EPOXIES FOR PAPER SIZING HERCULES INCORPORATED (US) 2000-07-13 WO claimed
EP-0239804-A1 Epoxy resins based on tetraglycidyl diamines and the use thereof for epoxy systems and prepregs AMOCO CORPORATION (US) 1987-10-07 EP claimed
EP-2451872-A1 CORE/SHELL RUBBERS FOR USE IN ELECTRICAL LAMINATE COMPOSITIONS Dow Global Technologies LLC (US) 2012-05-16 EP disclosed
WO-2011005925-A1 CORE/SHELL RUBBERS FOR USE IN ELECTRICAL LAMINATE COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2011-01-13 WO disclosed
EP-0362142-A2 Antistatic and electrically conductive composition CIBA-GEIGY AG (CH) 1990-04-04 EP disclosed
EP-0025178-B1 A COMPOSITION CONTAINING A HALF ESTER OF AN ORGANIC POLYOL, AN UNSATURATED MONOMER, AN EPOXIDE, AND REINFORCING FIBER UNION CARBIDE CORPORATION (US) 1984-10-03 EP disclosed