Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | P4HB | P07237 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338546 | 0.88 | PTGS2 (0.44) | PTGS2PTGS1RAB9AL3MBTL1MEN1 | |
| SCHEMBL10498066 | 0.86 | THRA (0.47) | MEN1KMT2ACYP1A2TDP1 | |
| SCHEMBL9338384 | 0.85 | MAOB (0.51) | RAB9AL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL9337818 | 0.85 | HDAC4 (0.45) | PTGS2P4HBPTGS1RAB9AMEN1 | |
| SCHEMBL9338665 | 0.82 | SLC6A19 (0.51) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9779017 | 0.82 | MAOB (0.48) | PTGS2PTGS1RAB9AMEN1KMT2A | |
| SCHEMBL9338586 | 0.81 | NPSR1 (0.48) | PTGS2PTGS1RAB9AMEN1KMT2A | |
| SCHEMBL9338406 | 0.80 | BCL2 (0.43) | PTGS2PTGS1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9338680 | 0.80 | HDAC4 (0.39) | PTGS2PTGS1RAB9AKMT2ALMNA | |
| SCHEMBL9339939 | 0.79 | MAOB (0.54) | MEN1KMT2ALMNAALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |