Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348177 | 0.90 | SLC6A9 (0.41) | SLC6A9MTNR1AMTNR1BPIN1PPARD | |
| SCHEMBL9509654 | 0.90 | MTNR1A (0.45) | SLC6A9MTNR1AMTNR1BPIN1PPARD | |
| SCHEMBL9345600 | 0.84 | PREP (0.36) | SLC6A9MTNR1AMTNR1BPIN1PDE10A | |
| SCHEMBL9348463 | 0.80 | SLC6A2 (0.35) | ALDH1A1KDM4EFFAR1 | |
| SCHEMBL9343742 | 0.77 | MTNR1B (0.36) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL11472819 | 0.70 | BLM (0.61) | MTNR1AMTNR1BPIN1FFAR1 | |
| SCHEMBL9348206 | 0.68 | MEN1 (0.36) | MTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL13834984 | 0.66 | SLC6A9 (0.50) | SLC6A9MTNR1AMTNR1BPPARDSIGMAR1 | |
| SCHEMBL7845908 | 0.66 | FFAR1 (0.62) | MTNR1AMTNR1BPPARDFFAR1 | |
| SCHEMBL7847075 | 0.66 | FFAR1 (0.62) | MTNR1AMTNR1BPPARDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1165538-A | — | — | None | — | — | JP | disclosed |
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |
| JP-H01165538-A | TETRALIN DERIVATIVE | SUNTORY LTD | 1989-06-29 | — | — | JP | disclosed |
| EP-0322248-A2 | Compounds effective against cerebral insufficiency | SUNTORY LIMITED (JP) | 1989-06-28 | — | — | EP | disclosed |