Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 4/20 | 0.34 |
| ▸ | EDNRB | P24530 | 3/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | FABP7 | O15540 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345540 | 0.75 | IDO1 (0.35) | MEN1KMT2ACYP3A4IDO1PKM | |
| SCHEMBL11002607 | 0.69 | TSHR (0.40) | MEN1KMT2AMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL9344193 | 0.68 | SLC6A9 (0.43) | MTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL8370379 | 0.67 | ALDH1A1 (0.42) | MEN1KMT2AMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL31065849 | 0.66 | ABAT (0.46) | TSHRSIGMAR1 | |
| SCHEMBL10810985 | 0.66 | ABAT (0.46) | TSHRSIGMAR1 | |
| SCHEMBL10611457 | 0.66 | FFAR1 (0.41) | MEN1KMT2AMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL9348177 | 0.65 | SLC6A9 (0.41) | MEN1KMT2AMTNR1AMTNR1BHTR2C | |
| Hydrochloric Acid SCHEMBL10810614 | 0.65 | SIGMAR1 (0.45) | TSHRSIGMAR1 | |
| SCHEMBL29443025 | 0.62 | AKR1C3 (0.50) | FABP5FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1197453-A | — | — | None | — | — | JP | disclosed |
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5179092-A | Cognition activators | SUNTORY LIMITED (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |
| JP-H01197453-A | CYCLOCONDENSATION QUINONE DERIVATIVE | SUNTORY LTD | 1989-08-09 | — | — | JP | disclosed |
| EP-0322248-A2 | Compounds effective against cerebral insufficiency | SUNTORY LIMITED (JP) | 1989-06-28 | — | — | EP | disclosed |