Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344193 | 0.90 | SLC6A9 (0.43) | SLC6A9MTNR1AMTNR1BPIN1PPARD | |
| SCHEMBL9343742 | 0.80 | MTNR1B (0.36) | MTNR1AMTNR1B | |
| SCHEMBL9509654 | 0.80 | MTNR1A (0.45) | SLC6A9MTNR1AMTNR1BPIN1PPARD | |
| SCHEMBL9345600 | 0.77 | PREP (0.36) | SLC6A9MTNR1AMTNR1BPIN1PDE10A | |
| SCHEMBL9348463 | 0.73 | SLC6A2 (0.35) | SLC6A3FFAR1MEN1KMT2A | |
| SCHEMBL4410486 | 0.70 | HTR2C (0.44) | MTNR1AMTNR1BPIN1HTR2CSLC6A3 | |
| SCHEMBL1567103 | 0.67 | MTNR1A (0.56) | MTNR1AMTNR1BPIN1HTR2CSLC6A3 | |
| SCHEMBL9348206 | 0.65 | MEN1 (0.36) | MTNR1AMTNR1BHTR2CMEN1KMT2A | |
| SCHEMBL27887145 | 0.65 | MTNR1A (0.39) | SLC6A9MTNR1AMTNR1B | |
| SCHEMBL11472819 | 0.63 | BLM (0.61) | MTNR1AMTNR1BPIN1HTR2CSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5179092-A | Cognition activators | SUNTORY LIMITED (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0322248-A2 | Compounds effective against cerebral insufficiency | SUNTORY LIMITED (JP) | 1989-06-28 | — | — | EP | disclosed |