Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 7/20 | 0.46 |
| ▸ | HTR2A | P28223 | 7/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | DRD1 | P21728 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | DRD5 | P21918 | 3/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349900 | 0.92 | TSHR (0.50) | ALOX15TSHRHTR1AHTR2ADRD2 | |
| SCHEMBL9344888 | 0.92 | TSHR (0.48) | ALOX15TSHRHTR1AHTR2AHTR7 | |
| SCHEMBL9346847 | 0.92 | TSHR (0.48) | ALOX15TSHRHTR1AHTR2ADRD2 | |
| SCHEMBL9349813 | 0.89 | TSHR (0.48) | ALOX15TSHRHTR1AHTR2ADRD2 | |
| SCHEMBL9349856 | 0.86 | HTR7 (0.49) | ALOX15TSHRHTR1AHTR2ADRD2 | |
| SCHEMBL9344861 | 0.86 | HTR1A (0.44) | HTR1AHTR2ADRD2DRD3DRD1 | |
| SCHEMBL9345654 | 0.82 | ALDH1A1 (0.50) | ALOX15TSHRHTR1AHTR2ADRD2 | |
| SCHEMBL9345630 | 0.82 | TSHR (0.48) | ALOX15TSHRHTR1AHTR2ADRD2 | |
| SCHEMBL9345579 | 0.82 | TSHR (0.51) | ALOX15TSHRHTR1AHTR2ADRD2 | |
| SCHEMBL9398295 | 0.81 | TSHR (0.53) | ALOX15TSHRHTR1AHTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326870-A | Asthma; bronchodilator agents; respiratory system disorders | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0525203-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVE OR PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1993-02-03 | — | — | EP | disclosed |