Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HRAS | P01112 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273856 | 0.81 | MEN1 (0.51) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL1018977 | 0.73 | CYP3A4 (0.42) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL21866586 | 0.73 | RAPGEF4 (0.43) | ALDH1A1GAAALPLALPILMNA | |
| SCHEMBL7130826 | 0.69 | HCAR3 (0.60) | ALDH1A1CYP3A4MAPK1MAPTHCAR3 | |
| SCHEMBL18299485 | 0.67 | RAPGEF4 (0.38) | ALDH1A1ALPLALPILMNASMN1; SMN2 | |
| SCHEMBL11372464 | 0.66 | LMNA (0.43) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL31497276 | 0.65 | TGM2 (0.53) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11676995 | 0.65 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL9345969 | 0.64 | MEN1 (0.49) | ALDH1A1CYP3A4TSHRTDP1HPGD | |
| SCHEMBL30406158 | 0.64 | MAPT (0.49) | ALDH1A1TDP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479384-B1 | Process for treating dinitroanilines with sulfite to reduce impurities and to reduce the ability to produce nitrosamines | DOWELANCO (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0479384-A1 | Process for treating dinitroanilines with sulfite to reduce impurities and to reduce the ability to produce nitrosamines | DOWELANCO (US) | 1992-04-08 | — | — | EP | disclosed |