Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861458 | 0.74 | GABRA1 (0.50) | CYP3A4ALOX15P2RX1MAPK1MAPT | |
| SCHEMBL11372464 | 0.74 | LMNA (0.43) | CYP3A4ALDH1A1TSHRTDP1ALOX15 | |
| SCHEMBL9345965 | 0.73 | ALDH1A1 (0.35) | CYP3A4ALDH1A1TSHRTDP1ALOX15 | |
| SCHEMBL9316398 | 0.71 | GPR35 (0.66) | CYP3A4ALDH1A1TSHRTDP1ALOX15 | |
| SCHEMBL19371270 | 0.70 | ALDH1A1 (0.50) | CYP3A4ALDH1A1TSHRTDP1ALOX15 | |
| SCHEMBL1018886 | 0.69 | ENPP2 (0.39) | ALDH1A1TDP1HPGDMAPK1MAPT | |
| SCHEMBL5861609 | 0.68 | CYP3A4 (0.47) | CYP3A4ALDH1A1TSHRTDP1ALOX15 | |
| SCHEMBL28057460 | 0.67 | FBP1 (0.47) | — | |
| SCHEMBL27751981 | 0.66 | ALDH1A1 (0.47) | ALDH1A1TDP1HPGDMAPK1MAPT | |
| SCHEMBL3012993 | 0.66 | TAAR1 (0.51) | ALDH1A1MAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8568685-B2 | Separation of nanostructures | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-29 | — | — | US | disclosed |
| US-20110011773-A1 | Separation of Nanostructures | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2011-01-20 | — | — | US | disclosed |
| EP-2225174-A2 | SEPARATION OF NANOSTRUCTURES | Massachusetts Institute of Technology (US) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009070240-A2 | SEPARATION OF NANOSTRUCTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-06-04 | — | — | WO | disclosed |