Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.40 |
| ▸ | GSR | P00390 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592225 | 0.80 | EPHX2 (0.51) | EPHX2HPGDALDH1A1POLBMEN1 | |
| SCHEMBL7926 | 0.79 | EPHX2 (0.49) | EPHX2HPGDALDH1A1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL28539557 | 0.77 | EPHX2 (0.48) | EPHX2HPGDALDH1A1POLBMEN1 | |
| SCHEMBL9498559 | 0.75 | ALOX15 (0.48) | EPHX2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11244833 | 0.75 | HDAC8 (0.52) | EPHX2HPGDALDH1A1POLBMEN1 | |
| SCHEMBL9349123 | 0.74 | EPHX2 (0.47) | EPHX2HPGDALDH1A1POLBMEN1 | |
| Fumaric Acid SCHEMBL9795340 | 0.72 | ALDH1A1 (0.43) | EPHX2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9344169 | 0.71 | TSHR (0.39) | EPHX2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9131095 | 0.71 | LMNA (0.36) | GSRBCHENAMPT | |
| SCHEMBL23927596 | 0.70 | GSR (0.42) | GSRALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280031-A | Cyclic azaaliphatic compounds with a nitroxy function, processes for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5030641-A | Treatment of angina pectoris, hypotensive agents | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-09 | — | — | US | disclosed |