Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 9/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331007 | 0.95 | KEAP1 (0.43) | KEAP1NFE2L2LMNATAS2R14MAPT | |
| SCHEMBL13223614 | 0.93 | KEAP1 (0.41) | KEAP1NFE2L2LMNATAS2R14MAPT | |
| SCHEMBL9348982 | 0.92 | KEAP1 (0.41) | KEAP1NFE2L2LMNATAS2R14MAPT | |
| SCHEMBL6363184 | 0.89 | KEAP1 (0.38) | KEAP1NFE2L2LMNATAS2R14MAPT | |
| SCHEMBL17268342 | 0.89 | MEN1 (0.39) | KEAP1NFE2L2LMNATAS2R14ALOX5 | |
| SCHEMBL18118852 | 0.89 | RAB9A (0.42) | KEAP1NFE2L2LMNAMAPTALDH1A1 | |
| SCHEMBL30180827 | 0.87 | KEAP1 (0.43) | KEAP1NFE2L2LMNATAS2R14MAPT | |
| SCHEMBL17260208 | 0.87 | KEAP1 (0.43) | KEAP1NFE2L2LMNATAS2R14MAPT | |
| SCHEMBL14400926 | 0.86 | LMNA (0.40) | KEAP1NFE2L2LMNAMAPTALDH1A1 | |
| SCHEMBL18114368 | 0.85 | KEAP1 (0.44) | KEAP1NFE2L2LMNATAS2R14KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273115-B1 | Chemiluminescent acridinium and phenanthridinium salts | ABBOTT LAB (US) | 1994-09-07 | — | — | EP | claimed |