Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348982 | 0.95 | KEAP1 (0.41) | KEAP1NFE2L2CNR2LMNAPOLB | |
| SCHEMBL19627075 | 0.92 | ALDH1A1 (0.42) | MEN1KMT2AATMKEAP1NFE2L2 | |
| SCHEMBL6363184 | 0.90 | KEAP1 (0.38) | MEN1KMT2AKEAP1NFE2L2LMNA | |
| SCHEMBL2331007 | 0.90 | KEAP1 (0.43) | MEN1KMT2AKEAP1NFE2L2CNR2 | |
| SCHEMBL9350381 | 0.89 | KEAP1 (0.43) | MEN1KMT2AKEAP1NFE2L2LMNA | |
| SCHEMBL13223614 | 0.89 | KEAP1 (0.41) | KMT2AKEAP1NFE2L2TDP1LMNA | |
| SCHEMBL14400926 | 0.88 | LMNA (0.40) | MEN1KMT2AKEAP1NFE2L2LMNA | |
| SCHEMBL18114368 | 0.84 | KEAP1 (0.44) | MEN1KMT2AKEAP1NFE2L2CNR2 | |
| SCHEMBL18118867 | 0.84 | LMNA (0.34) | MEN1KMT2AKEAP1NFE2L2LMNA | |
| SCHEMBL18118852 | 0.83 | RAB9A (0.42) | MEN1KMT2AKEAP1NFE2L2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150330986-A1 | COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME | ABBOTT LAB (US) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150330986-A1 | COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME | APOB, MPO, LPO | MEN1 3484/4885KMT2A 4540/4885ATM 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.