Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 5/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17268342 | 0.95 | MEN1 (0.39) | KEAP1NFE2L2LMNATAS2R14CNR2 | |
| SCHEMBL2331007 | 0.93 | KEAP1 (0.43) | KEAP1NFE2L2LMNATAS2R14GAA | |
| SCHEMBL6363184 | 0.93 | KEAP1 (0.38) | KEAP1NFE2L2LMNATAS2R14GAA | |
| SCHEMBL9350381 | 0.92 | KEAP1 (0.43) | KEAP1NFE2L2LMNATAS2R14ALDH1A1 | |
| SCHEMBL13223614 | 0.91 | KEAP1 (0.41) | KEAP1NFE2L2LMNATAS2R14ALDH1A1 | |
| SCHEMBL14400926 | 0.87 | LMNA (0.40) | KEAP1NFE2L2LMNAALDH1A1POLB | |
| SCHEMBL19627075 | 0.87 | ALDH1A1 (0.42) | KEAP1NFE2L2GAAKDM4EALDH1A1 | |
| SCHEMBL18118867 | 0.87 | LMNA (0.34) | KEAP1NFE2L2LMNAGAAALDH1A1 | |
| SCHEMBL13926065 | 0.85 | KEAP1 (0.33) | KEAP1NFE2L2LMNAALDH1A1POLB | |
| SCHEMBL18118858 | 0.85 | RAB9A (0.40) | LMNAALDH1A1POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273115-B1 | Chemiluminescent acridinium and phenanthridinium salts | ABBOTT LAB (US) | 1994-09-07 | — | — | EP | claimed |