SCHEMBL2331007

SCHEMBL2331007

Cc1ccc(S(=O)(=O)N(CCCC(=O)O)C(=O)c2c3ccccc3[n+](CCCS(=O)(=O)O)c3ccccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 7/20 0.43
NFE2L2 Q16236 7/20 0.43
LMNA P02545 1/20 0.38
TAS2R14 Q9NYV8 1/20 0.35
C1R P00736 1/20 0.34
PRSS1 P07477 1/20 0.34
MAPT P10636 1/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13223614 0.96 KEAP1 (0.41) KEAP1NFE2L2LMNATAS2R14MAPT
SCHEMBL9350381 0.95 KEAP1 (0.43) KEAP1NFE2L2LMNATAS2R14MAPT
SCHEMBL9348982 0.93 KEAP1 (0.41) KEAP1NFE2L2LMNATAS2R14MAPT
SCHEMBL30180827 0.92 KEAP1 (0.43) KEAP1NFE2L2LMNATAS2R14MAPT
SCHEMBL17260208 0.92 KEAP1 (0.43) KEAP1NFE2L2LMNATAS2R14MAPT
SCHEMBL6363184 0.92 KEAP1 (0.38) KEAP1NFE2L2LMNATAS2R14C1R
SCHEMBL18118852 0.92 RAB9A (0.42) KEAP1NFE2L2LMNAMAPTMEN1
SCHEMBL17268342 0.90 MEN1 (0.39) KEAP1NFE2L2LMNATAS2R14MEN1
SCHEMBL18114368 0.90 KEAP1 (0.44) KEAP1NFE2L2LMNATAS2R14MEN1
SCHEMBL2329207 0.88 KEAP1 (0.40) KEAP1NFE2L2LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170336416-A1 COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME ABBOTT LABORATORIES 2017-11-23 US claimed
US-20150330986-A1 COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME ABBOTT LAB (US) 2015-11-19 US claimed
EP-3523640-B1 DEVICES FOR SAMPLE ANALYSIS ABBOTT LAB (US) 2023-01-18 EP disclosed
EP-3523640-B1 DEVICES FOR SAMPLE ANALYSIS ABBOTT LAB (US) 2023-01-18 EP disclosed
US-20210325334-A1 Devices and Methods for Sample Analysis ABBOTT LABORATORIES 2021-10-21 US disclosed
EP-3839507-A1 DEVICES AND METHODS FOR SAMPLE ANALYSIS Abbott Laboratories (US) 2021-06-23 EP disclosed
US-11022598-B2 Devices and methods for sample analysis ABBOTT LABORATORIES (US) 2021-06-01 US disclosed
US-11016053-B2 Devices and methods for sample analysis ABBOTT LABORATORIES (US) 2021-05-25 US disclosed
EP-3278108-B1 DEVICES AND METHODS FOR SAMPLE ANALYSIS ABBOTT LAB (US) 2021-03-17 EP disclosed
EP-3278108-B1 DEVICES AND METHODS FOR SAMPLE ANALYSIS ABBOTT LAB (US) 2021-03-17 EP disclosed
US-20200256843-A1 DEVICES AND METHODS FOR SAMPLE ANALYSIS ABBOTT LABORATORIES (US) 2020-08-13 US disclosed
US-20080206788-A1 Reagents and methods for the detection and quantification of vancomycin in biological fluids ADAMCZYK MACIEJ 2008-08-28 US disclosed
US-7319041-B2 Applications of acridinium compounds and derivatives in homogeneous assays SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) 2008-01-15 US disclosed
EP-1121599-B1 DETECTION AND QUANTIFICATION OF VANCOMYCIN IN BIOLOGICAL FLUIDS ABBOTT LAB (US) 2004-12-15 EP disclosed
US-20040209318-A1 Reagents and methods for the detection and quantification of vancomycin in bilogical fluids ADAMCZYK MACIEJ (US) 2004-10-21 US disclosed
US-6797479-B2 IMMUNOASSAY REAGENTS, METHODS AND TEST KITS; ANTIBODY REAGENT PRODUCED WITH IMMUNOGEN-CONJUGATED VANCOMYCIN, A LABELED VANCOMYCIN REAGENT WHICH IS CAPABLE OR DISPLACING THE BINDING OF THE ANTIBODY TO VANCOMYCIN, AND STABLE CALIBRATOR ABBOTT LABORATORIES 2004-09-28 US disclosed
US-20020009708-A1 REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF VANCOMYCIN IN BIOLOGICAL FLUIDS ABBOTT LABORATORIES 2002-01-24 US disclosed
EP-1121599-A1 DETECTION AND QUANTIFICATION OF VANCOMYCIN IN BIOLOGICAL FLUIDS ABBOTT LABORATORIES (US) 2001-08-08 EP disclosed
WO-2000023806-A9 DETECTION AND QUANTIFICATION OF VANCOMYCIN IN BIOLOGICAL FLUIDS ABBOTT LAB (US) 2000-10-26 WO disclosed
WO-2000023806-A1 DETECTION AND QUANTIFICATION OF VANCOMYCIN IN BIOLOGICAL FLUIDS ABBOTT LABORATORIES (US) 2000-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150330986-A1 COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME APOB, MPO, LPO KEAP1 1733/4885NFE2L2 885/4885LMNA 813/4885
US-20170336416-A1 COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME APOB, MPO, LPO KEAP1 1733/4885NFE2L2 885/4885LMNA 813/4885
US-20080206788-A1 Reagents and methods for the detection and quantification of vancomycin in biological fluids SERPINA6, CD4, VSIR KEAP1 2298/4885NFE2L2 4778/4885LMNA 2072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.