Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576616 | 0.96 | LMNA (0.34) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10576609 | 0.89 | LMNA (0.31) | LMNAKDM4EHSD17B10 | |
| SCHEMBL499915 | 0.81 | HSPA5 (0.40) | LMNANFKB1ALDH1A1NPSR1 | |
| SCHEMBL9356038 | 0.81 | APEX1 (0.40) | EGFRTDP1L3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL29061736 | 0.80 | ALDH1A1 (0.33) | LMNAKDM4EGAANFKB1HTT | |
| SCHEMBL77036 | 0.80 | SMN1; SMN2 (0.39) | CA2POLBSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL379576 | 0.80 | RXRA (0.33) | GAAHTTALDH1A1PPARGNPSR1 | |
| SCHEMBL6745877 | 0.80 | GAA (0.40) | GAAMAPT | |
| Phosphine SCHEMBL3163238 | 0.79 | SMN1; SMN2 (0.38) | CA2POLBSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL10774866 | 0.79 | THRB (0.35) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186628-B1 | PENTAERYTHRITDIPHOSPHITES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS STABILIZERS | CIBA-GEIGY AG (CH) | 1989-12-13 | — | — | EP | claimed |
| JP-1009252-A | — | — | None | — | — | JP | disclosed |
| JP-S649252-A | RADIATION-RESISTANT POLYOLEFIN COMPOSITION | ADEKA ARGUS CHEMICAL CO LTD | 1989-01-12 | — | — | JP | disclosed |