Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | PGK2 | P07205 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826259 | 1.00 | ADORA1 (0.51) | ADORA1ADORA3POLA1PGK1PGK2 | |
| SCHEMBL8826282 | 0.88 | CYP1A2 (0.47) | ADORA1ADORA3PGK1PGK2PNP | |
| SCHEMBL8826379 | 0.88 | TDP1 (0.50) | ADORA1ADORA3PGK1PGK2ADORA2A | |
| SCHEMBL9542046 | 0.83 | ADORA3 (0.63) | ADORA1ADORA3PGK1PGK2PNP | |
| SCHEMBL8826290 | 0.83 | ADORA3 (0.63) | ADORA1ADORA3PGK1PGK2PNP | |
| SCHEMBL8939245 | 0.81 | PNP (0.48) | ADORA1ADORA3PNPLMNATP53 | |
| SCHEMBL8826235 | 0.80 | PGK1 (0.55) | ADORA1ADORA3PGK1PGK2PNP | |
| SCHEMBL8830311 | 0.80 | NR1I2 (0.60) | PDE4D | |
| SCHEMBL8826210 | 0.80 | PGK1 (0.56) | ADORA1ADORA3PGK1PGK2PNP | |
| SCHEMBL8826529 | 0.78 | PGK1 (0.50) | ADORA1ADORA3PGK1PGK2PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625158-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-23 | — | — | EP | disclosed |