Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358391 | 0.87 | TRPA1 (0.40) | LMNAGBA1 | |
| SCHEMBL9358293 | 0.83 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1KMT2ACYP3A4 | |
| SCHEMBL9358356 | 0.81 | GBA1 (0.36) | MEN1KMT2AALOX15GBA1 | |
| SCHEMBL9358596 | 0.81 | ABCB1 (0.43) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL9362699 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL9358363 | 0.80 | NR1H4 (0.35) | ALDH1A1MAPTCYP3A4HSD17B10 | |
| SCHEMBL9358568 | 0.78 | RBP4 (0.31) | LMNAALOX15 | |
| SCHEMBL9358347 | 0.77 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL11145337 | 0.75 | LMNA (0.35) | LMNAALOX15 | |
| SCHEMBL10582848 | 0.68 | GAA (0.38) | ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518197-B1 | Piperidine derivatives | MITSUBISHI PETROCHEMICAL CO (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5260443-A | For polyolefin films | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5189172-A | Useful as photostabilizer or as intermediates for pharmaceuticals and agricultural chemicals | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0518197-A1 | Piperidine derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-16 | — | — | EP | disclosed |