Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358209 | 0.81 | LMNA (0.38) | GBA1ALOX15KMT2AMEN1 | |
| SCHEMBL9358391 | 0.77 | TRPA1 (0.40) | GBA1GRIN2BGAA | |
| SCHEMBL9362686 | 0.73 | ALOX15 (0.52) | GBA1CYP2D6SLC6A2SLC6A4DRD2 | |
| SCHEMBL11145337 | 0.72 | LMNA (0.35) | ALOX15 | |
| SCHEMBL9358293 | 0.71 | ALDH1A1 (0.36) | ALOX15KMT2AMEN1 | |
| SCHEMBL9358363 | 0.71 | NR1H4 (0.35) | — | |
| SCHEMBL10582848 | 0.66 | GAA (0.38) | GAA | |
| SCHEMBL9362699 | 0.63 | ALDH1A1 (0.44) | ALOX15KMT2AMEN1 | |
| SCHEMBL9039574 | 0.63 | KMT2A (0.41) | GBA1GRIN2BACHEKMT2ACYP2A13 | |
| SCHEMBL9358658 | 0.63 | ALDH1A1 (0.32) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518197-B1 | Piperidine derivatives | MITSUBISHI PETROCHEMICAL CO (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5260443-A | For polyolefin films | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5189172-A | Useful as photostabilizer or as intermediates for pharmaceuticals and agricultural chemicals | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0518197-A1 | Piperidine derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-16 | — | — | EP | disclosed |