Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218035 | 0.88 | KDM4E (0.49) | KDM4EALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL217496 | 0.85 | NNMT (0.49) | KDM4EALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL4504976 | 0.75 | GRM5 (0.53) | KDM4EALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL31132753 | 0.74 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTLMNARAB9A | |
| SCHEMBL476528 | 0.74 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTLMNARAB9A | |
| SCHEMBL13977996 | 0.74 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL4070958 | 0.72 | HCAR3 (0.63) | KDM4EALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL29424855 | 0.72 | NNMT (0.54) | SMN1; SMN2NNMTHDAC6 | |
| SCHEMBL2487358 | 0.72 | NNMT (0.54) | SMN1; SMN2NNMTHDAC6 | |
| SCHEMBL28117859 | 0.72 | NNMT (0.46) | SMN1; SMN2GAANNMTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341886-B1 | Aqueous coating compositions | ZENECA RESINS BV (NL) | 1994-12-07 | — | — | EP | disclosed |
| US-4988762-A | Crosslinking coating comprising aziridine-modified addition polymers having pendant ketones or aldehydes; protective coatings; adhesives; imination | ICI RESINS B.V. (NL) | 1991-01-29 | — | — | US | disclosed |
| EP-0341886-A2 | Aqueous coating compositions | ZENECA RESINS BV (NL) | 1989-11-15 | — | — | EP | disclosed |