Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217496 | 0.85 | NNMT (0.49) | NNMTHCAR3HDAC1HDAC6 | |
| SCHEMBL29424855 | 0.82 | NNMT (0.54) | NNMTHCAR3HDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL2487358 | 0.82 | NNMT (0.54) | NNMTHCAR3HDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL29505896 | 0.79 | HCAR3 (0.67) | HCAR3 | |
| SCHEMBL158601 | 0.79 | HCAR3 (0.67) | HCAR3 | |
| SCHEMBL8722229 | 0.79 | NNMT (0.50) | NNMTHCAR3GAA | |
| SCHEMBL383413 | 0.79 | NNMT (0.70) | NNMTHCAR3SMN1; SMN2 | |
| SCHEMBL12388325 | 0.78 | HCAR3 (0.51) | NNMTHCAR3 | |
| SCHEMBL22403855 | 0.78 | NNMT (0.46) | NNMTHCAR3HDAC1HDAC6DEGS1 | |
| SCHEMBL8126559 | 0.78 | NNMT (0.42) | NNMTHCAR3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732595-B | Folate conjugates of albumin-binding entities | 默克及其合伙人公司 | 2017-02-08 | — | — | CN | disclosed |