Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849709 | 0.81 | LMNA (0.38) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL28564265 | 0.78 | THRB (0.52) | ALDH1A1MAPTLMNAHTTMEN1 | |
| SCHEMBL28572444 | 0.76 | GAA (0.47) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL9255856 | 0.76 | ALDH1A1 (0.53) | ALDH1A1CTSLCTSSCTSKMAPT | |
| SCHEMBL6334634 | 0.73 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL30288272 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAHTTKDM4E | |
| SCHEMBL16625291 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL1965817 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL108260 | 0.72 | ALDH1A1 (0.42) | ALDH1A1CTSLCTSSCTSKMAPT | |
| SCHEMBL8987992 | 0.70 | PTGER4 (0.41) | ALDH1A1MAPTLMNAHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412529-B1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5091403-A | SULFINYL IMIDAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING THE SAME | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0412529-A1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |