Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 8/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL575589 | 0.87 | CA2 (0.52) | MMP2MMP7MMP9MMP14MMP1 | |
| SCHEMBL3838977 | 0.80 | CA2 (0.58) | MMP2MMP7MMP9MMP14MMP1 | |
| SCHEMBL6941035 | 0.78 | CA1 (0.64) | MMP2MMP7MMP9MMP14MMP1 | |
| SCHEMBL168170 | 0.78 | CA2 (0.64) | MMP2MMP7MMP9MMP14MMP1 | |
| Hydrochloric Acid SCHEMBL11580385 | 0.76 | CA2 (0.61) | MMP2MMP7MMP9MMP14MMP1 | |
| SCHEMBL4172581 | 0.76 | CA2 (0.61) | MMP2MMP7MMP9MMP14MMP1 | |
| SCHEMBL6037 | 0.76 | CA2 (0.48) | MMP2MMP7MMP9MMP14MMP1 | |
| SCHEMBL1353639 | 0.76 | MMP2 (0.43) | MMP2MMP7MMP9MMP14MMP1 | |
| SCHEMBL4609033 | 0.76 | CA2 (0.61) | MMP2MMP7MMP9MMP14MMP1 | |
| SCHEMBL2000447 | 0.76 | ALDH1A1 (0.52) | MMP2MMP7MMP9MMP14MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54098325-A | — | — | None | — | — | JP | disclosed |
| JP-62089655-A | — | — | None | — | — | JP | disclosed |
| US-10961231-B2 | NTCP inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-03-30 | — | — | US | disclosed |
| US-10961231-B2 | NTCP inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-03-30 | — | — | US | disclosed |
| US-20210040072-A1 | NTCP Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-02-11 | — | — | US | disclosed |
| US-20210040072-A1 | NTCP Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-02-11 | — | — | US | disclosed |
| EP-3765482-A1 | NTCP INHIBITORS | National Institute Of Biological Sciences, Beijing (CN) | 2021-01-20 | — | — | EP | disclosed |
| WO-2020215267-A1 | USE OF NTCP INHIBITORS IN PREVENTING AND TREATING HEPATOCARCINOGENESIS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2020-10-29 | — | — | WO | disclosed |
| WO-2019196953-A1 | NTCP INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2019-10-17 | — | — | WO | disclosed |
| US-8470860-B2 | Phenyl-sulfamates as aromatase inhibitors | STERIX LIMITED (GB) | 2013-06-25 | — | — | US | disclosed |
| US-20070117855-A1 | Phenyl-sulfamates as aromatase inhibitors | STERIX LIMITED (GB) | 2007-05-24 | — | — | US | disclosed |
| US-20070117855-A1 | Phenyl-sulfamates as aromatase inhibitors | STERIX LIMITED (GB) | 2007-05-24 | — | — | US | disclosed |
| EP-1753732-A1 | PHENYL-SULFAMATES AS AROMATASE INHIBITORS | Sterix Limited (GB) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005118560-A1 | PHENYL-SULFAMATES AS AROMATASE INHIBITORS | STERIX LIMITED (GB) | 2005-12-15 | — | — | WO | disclosed |
| JP-S6289655-A | 4,4'-DITHIOBIS(METHANESULFONYLOXYBENZENE) | SEITETSU KAGAKU CO LTD | 1987-04-24 | — | — | JP | disclosed |
| US-4211785-A | Fungicidal composition for use in agriculture and horticulture and its use | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-07-08 | — | — | US | disclosed |
| JP-S5498325-A | AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION | NIPPON KAYAKU CO LTD | 1979-08-03 | — | — | JP | disclosed |
| US-4126696-A | 4-ALKYLSULFONYLOXYPHENYL N-ALKYLTHIOLCARBAMATES AND USE THEREOF AS FUNGICIDE FOR AGRICULTURE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1978-11-21 | — | — | US | disclosed |
| US-4086360-A | Phenyl thiol carbanilide derivatives, method for the preparation thereof and use thereof as fungicide for agriculture | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1978-04-25 | — | — | US | disclosed |
| US-4086337-A | O,S-dialkyl O(S)-sulfonyloxy(thio)phenyl phosphorothiolates and phosphorodi(tri)thioates | ROHM AND HAAS COMPANY (US) | 1978-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040072-A1 | NTCP Inhibitors | HAVCR2, NPC1, HMGCR | MMP2 4090/4885MMP7 3545/4885MMP9 4164/4885 |
| US-20070117855-A1 | Phenyl-sulfamates as aromatase inhibitors | CYP19A1, CYP17A1, CYP21A2 | MMP2 1128/4885MMP7 2199/4885MMP9 1314/4885 |
| US-10961231-B2 | NTCP inhibitors | HAVCR2, NPC1, HMGCR | MMP2 4090/4885MMP7 3545/4885MMP9 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.