Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622905 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2GAATSHRLMNAMAPT | |
| SCHEMBL9367286 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2GAATSHRLMNAMAPT | |
| SCHEMBL9367280 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2GAATSHRLMNAMAPT | |
| SCHEMBL9622236 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2GAATSHRLMNAMAPT | |
| SCHEMBL9622231 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2GAATSHRLMNAMAPT | |
| Fumaric Acid SCHEMBL9622178 | 0.80 | ALDH1A1 (0.49) | SMN1; SMN2GAATSHRLMNAMAPT | |
| Fumaric Acid SCHEMBL9622181 | 0.80 | ALDH1A1 (0.49) | SMN1; SMN2GAATSHRLMNAMAPT | |
| Fumaric Acid SCHEMBL9622176 | 0.80 | ALDH1A1 (0.49) | SMN1; SMN2GAATSHRLMNAMAPT | |
| SCHEMBL9622597 | 0.76 | LMNA (0.44) | SMN1; SMN2TSHRLMNAMAPTMAPK1 | |
| SCHEMBL9622599 | 0.76 | LMNA (0.44) | SMN1; SMN2TSHRLMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126356-A | Antiischemic agents | ADIR ET COMPAGNIE (FR) | 1992-06-30 | — | — | US | disclosed |