Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622231 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MCHR1LMNAGAA | |
| SCHEMBL9622908 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1MCHR1LMNAGAA | |
| SCHEMBL9622905 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1MCHR1LMNAGAA | |
| SCHEMBL9367280 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MCHR1LMNAGAA | |
| SCHEMBL9367286 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MCHR1LMNAGAA | |
| Fumaric Acid SCHEMBL9622181 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MCHR1LMNAGAA | |
| Fumaric Acid SCHEMBL9622178 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MCHR1LMNAGAA | |
| Fumaric Acid SCHEMBL9622176 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MCHR1LMNAGAA | |
| SCHEMBL9622597 | 0.74 | LMNA (0.44) | SMN1; SMN2ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL9622599 | 0.74 | LMNA (0.44) | SMN1; SMN2ALDH1A1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126356-A | Antiischemic agents | ADIR ET COMPAGNIE (FR) | 1992-06-30 | — | — | US | disclosed |