Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6099384 | 0.86 | ALDH1A1 (0.46) | HTTSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL1020142 | 0.85 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL30134039 | 0.85 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL113562 | 0.85 | KEAP1 (0.53) | PIN1HTTSMN1; SMN2LMNARAB9A | |
| SCHEMBL29622845 | 0.85 | KEAP1 (0.53) | PIN1HTTSMN1; SMN2LMNARAB9A | |
| SCHEMBL16952707 | 0.84 | PIN1 (0.44) | PIN1HTTSMN1; SMN2LMNARAB9A | |
| SCHEMBL5756844 | 0.83 | CFD (0.51) | HTTSMN1; SMN2LMNARAB9AALDH1A1 | |
| SCHEMBL2328719 | 0.83 | PIN1 (0.48) | PIN1HTTSMN1; SMN2LMNARAB9A | |
| SCHEMBL4300383 | 0.83 | SMN1; SMN2 (0.52) | PIN1HTTSMN1; SMN2LMNARAB9A | |
| SCHEMBL29406733 | 0.83 | PIN1 (0.50) | PIN1HTTSMN1; SMN2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028600-A1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12448611-B2 | Transaminase polypeptides | CODEXIS, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| US-12378537-B2 | Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs | CODEXIS, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| US-12305201-B2 | Engineered biocatalysts and methods for synthesizing chiral amines | CODEXIS, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| WO-2025099238-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF GASTROINTESTINAL STROMAL TUMOR (GIST) | Universität Duisburg-Essen (DE) | 2025-05-15 | — | — | WO | disclosed |
| EP-4552639-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF GASTROINTESTINAL STROMAL TUMOR (GIST) | Universität Duisburg-Essen (DE) | 2025-05-14 | — | — | EP | disclosed |
| US-20250101389-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS | CODEXIS INC (US) | 2025-03-27 | — | — | US | disclosed |
| CN-119698468-A | Biocatalysts and methods thereof | 特沙诺有限公司 | 2025-03-25 | — | — | CN | disclosed |
| US-12163162-B2 | Biocatalysts and methods for the synthesis of substituted lactams | CODEXIS, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| US-20240150732-A1 | TRANSAMINASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2024-05-09 | — | — | US | disclosed |
| EP-1075534-B1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2005-05-11 | — | — | EP | disclosed |
| WO-2005012256-A1 | 3, 4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASES (CDK) AND GLYCOGEN SYNTHASE KINASE-3 (GSK-3) MODULATORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |
| EP-1075534-A4 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-1075534-A1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | Celgro (US) | 2001-02-14 | — | — | EP | disclosed |
| US-6133018-A | Enzymatic synthesis of chiral amines using -2-amino propane as amine donor | CELGRO (US) | 2000-10-17 | — | — | US | disclosed |
| WO-1999046398-A1 | IMPROVEMENTS IN THE ENZYMATIC SYNTHESIS OF CHIRAL AMINES | CELGRO (US) | 1999-09-16 | — | — | WO | disclosed |
| EP-0203791-B1 | SPIRO-IMIDAZOLIDINES AS ALDOSE REDUCTASE INHIBITORS | PFIZER INC. (US) | 1989-09-13 | — | — | EP | disclosed |
| EP-0203791-A1 | Spiro-imidazolidines as aldose reductase inhibitors | PFIZER INC. (US) | 1986-12-03 | — | — | EP | disclosed |
| US-4575507-A | COMPLICATIONS OF DIABETES | PFIZER INC. (US) | 1986-03-11 | — | — | US | disclosed |
| US-4251546-A | Process for killing internal helminths using certain 1,1-bis-(2-substituted-3-nitrophenyl)alkane or alkylene derivatives | ICI AUSTRALIA LIMITED (AU) | 1981-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250101389-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF SUBSTITUTED LACTAMS | BCAT1, GOT1, OAT | PIN1 726/4885HTT 4375/4885SMN1; SMN2 2789/4885 |
| US-20260028600-A1 | TRANSAMINASE POLYPEPTIDES | GOT1, OAT, PEPD | PIN1 568/4885HTT 3072/4885SMN1; SMN2 2464/4885 |
| US-12163162-B2 | Biocatalysts and methods for the synthesis of substituted lactams | BCAT1, GOT1, OAT | PIN1 726/4885HTT 4375/4885SMN1; SMN2 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.