Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368700 | 0.83 | PTPN1 (0.47) | MAPTALDH1A1PTPN1KMT2ATDP1 | |
| SCHEMBL9373488 | 0.83 | PTPN1 (0.51) | ALDH1A1PTPN1KMT2APPARACRHBP | |
| SCHEMBL10106410 | 0.76 | PTPN1 (0.58) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9538619 | 0.74 | NR3C1 (0.46) | MAPTSMN1; SMN2PTPN1KMT2ATDP1 | |
| SCHEMBL9369316 | 0.73 | MEP1B (0.50) | PTPN1 | |
| SCHEMBL21377435 | 0.72 | PTPN1 (0.64) | RAB9AMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9372770 | 0.70 | SLC7A5 (0.46) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL5335214 | 0.70 | MAPT (0.63) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL6653627 | 0.70 | L3MBTL1 (0.61) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL10145069 | 0.69 | CYP4F2 (0.52) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |