Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374271 | 0.87 | HTR1A (0.46) | HTR1ADRD2HTR2AMCHR1HTR7 | |
| SCHEMBL9369075 | 0.87 | HTR1A (0.46) | HTR1ADRD2HTR2AMCHR1HTR7 | |
| SCHEMBL9369796 | 0.87 | HTR1A (0.49) | L3MBTL1HTR1ADRD2HTR2AMCHR1 | |
| SCHEMBL9375687 | 0.85 | HTR1A (0.55) | HTR1ADRD2HTR2AMCHR1HTR7 | |
| SCHEMBL9371919 | 0.85 | DRD2 (0.58) | ALDH1A1MAPTHTR1ADRD2HTR2A | |
| SCHEMBL9377218 | 0.85 | POLB (0.50) | L3MBTL1ALDH1A1LMNADRD2HTR2A | |
| SCHEMBL9371801 | 0.84 | HTR1A (0.54) | HTR1ADRD2HTR2AMCHR1HTR7 | |
| SCHEMBL9369754 | 0.83 | SIGMAR1 (0.56) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9370355 | 0.83 | LMNA (0.47) | L3MBTL1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL9372262 | 0.83 | SIGMAR1 (0.56) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376633-B1 | Benzoxazepine derivatives | SUNTORY LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| EP-0376633-A2 | Benzoxazepine derivatives | SUNTORY LIMITED (JP) | 1990-07-04 | — | — | EP | disclosed |