Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382376 | 0.80 | RAB9A (0.55) | ALDH1A1HSD17B10RAB9AMAPTTP53 | |
| SCHEMBL9376802 | 0.80 | DRD2 (0.41) | HSD17B10RAB9AMAPTNSD1NPC1 | |
| SCHEMBL9376147 | 0.76 | HSD17B10 (0.43) | ALDH1A1HSD17B10RAB9AMAPTNSD1 | |
| SCHEMBL2920238 | 0.70 | NSD1 (0.50) | ALDH1A1HSD17B10RAB9AMAPTNSD1 | |
| SCHEMBL9376768 | 0.68 | GFER (0.48) | RAB9AMAPTTP53SMN1; SMN2NPC1 | |
| SCHEMBL2271143 | 0.68 | HSD17B10 (0.68) | ALDH1A1HSD17B10RAB9AMAPTTP53 | |
| SCHEMBL9375658 | 0.67 | NOS3 (0.42) | HSD17B10RAB9ATP53HPGDSMN1; SMN2 | |
| SCHEMBL2912621 | 0.66 | RAB9A (0.45) | ALDH1A1HSD17B10RAB9AMAPTHPGD | |
| SCHEMBL21177806 | 0.66 | CYP3A4 (0.46) | ALDH1A1HSD17B10RAB9AMAPTTP53 | |
| SCHEMBL9377356 | 0.66 | RAB9A (0.41) | RAB9AMAPTSMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |