Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | PI4KA | P42356 | 4/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376802 | 0.81 | DRD2 (0.41) | HSD17B10RAB9AMAPTNSD1PIK3CA | |
| SCHEMBL9379203 | 0.80 | RAB9A (0.60) | HSD17B10RAB9AMAPTPIK3CAPI4KA | |
| SCHEMBL9375337 | 0.76 | ALDH1A1 (0.42) | HSD17B10RAB9AMAPTNSD1PI4KA | |
| SCHEMBL2271143 | 0.72 | HSD17B10 (0.68) | HSD17B10RAB9AMAPTPDE10ANSD1 | |
| SCHEMBL2920238 | 0.71 | NSD1 (0.50) | HSD17B10RAB9AMAPTPDE10ANSD1 | |
| SCHEMBL19204656 | 0.68 | PDE10A (0.45) | PDE10ADHFRNOS1NOS2 | |
| SCHEMBL18682734 | 0.68 | CCR1 (0.52) | RAB9AMAPTPDE10ANOS2 | |
| SCHEMBL9375877 | 0.68 | GFER (0.50) | RAB9APDE10ANPC1DHFRNOS2 | |
| SCHEMBL2912621 | 0.68 | RAB9A (0.45) | HSD17B10RAB9AMAPTNSD1NPC1 | |
| SCHEMBL18512509 | 0.67 | PDE10A (0.46) | PDE10AALDH1A1DHFRNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |