Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PI4KA | P42356 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376415 | 0.82 | CYP3A4 (0.48) | DRD2KCNH2CYP1A2CYP2D6L3MBTL1 | |
| SCHEMBL9376147 | 0.81 | HSD17B10 (0.43) | PIK3CDPI4KAPIK3CGPI4KBPIK3CA | |
| SCHEMBL9375337 | 0.80 | ALDH1A1 (0.42) | PIK3CDPI4KAPIK3CGPI4KBNSD1 | |
| SCHEMBL9376809 | 0.78 | PI4KA (0.56) | DRD2KCNH2CYP2D6PIK3CDPI4KA | |
| SCHEMBL21638261 | 0.73 | ASIC3 (0.46) | DRD2KCNH2HRH1PIK3CDPI4KA | |
| SCHEMBL2920238 | 0.72 | NSD1 (0.50) | PI4KAPI4KBPIK3CANSD1HSD17B10 | |
| SCHEMBL8548182 | 0.71 | DRD2 (0.41) | DRD2KCNH2CYP2D6HRH1PIK3CD | |
| SCHEMBL9375983 | 0.69 | RAB9A (0.62) | DRD2KCNH2CYP2D6PIK3CDPI4KA | |
| SCHEMBL2912621 | 0.69 | RAB9A (0.45) | DRD2KCNH2NSD1HSD17B10NPC1 | |
| SCHEMBL28055776 | 0.68 | NSD1 (0.45) | CYP1A2NSD1HSD17B10CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |