Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040773 | 0.88 | MTNR1A (0.43) | MTNR1AMTNR1BPIN1CA1CA2 | |
| SCHEMBL7117287 | 0.84 | L3MBTL1 (0.45) | MTNR1AMTNR1BPIN1CA1CA2 | |
| SCHEMBL7109070 | 0.84 | L3MBTL1 (0.45) | MTNR1AMTNR1BPIN1CA1CA2 | |
| SCHEMBL6496701 | 0.83 | CHRM2 (0.47) | MTNR1AMTNR1BPIN1DRD2DRD3 | |
| SCHEMBL6627932 | 0.83 | CHRM2 (0.47) | MTNR1AMTNR1BPIN1DRD2DRD3 | |
| SCHEMBL9379681 | 0.81 | ALDH1A1 (0.46) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL7557806 | 0.81 | LTB4R (0.47) | MTNR1AMTNR1BPIN1CA1CA2 | |
| SCHEMBL7552940 | 0.81 | LTB4R (0.47) | MTNR1AMTNR1BPIN1CA1CA2 | |
| SCHEMBL7552930 | 0.81 | LTB4R (0.47) | MTNR1AMTNR1BPIN1CA1CA2 | |
| Hydrochloric Acid SCHEMBL8858324 | 0.80 | LTB4R (0.47) | MTNR1AMTNR1BPIN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352613-B1 | Substituted amino methyl tetralines, and their heterocyclic analogous compounds | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| EP-0352613-A2 | Substituted amino methyl tetralines, and their heterocyclic analogous compounds | BAYER AG (DE) | 1990-01-31 | — | — | EP | disclosed |