Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | DRD3 | P35462 | 6/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627932 | 1.00 | CHRM2 (0.47) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL4224918 | 0.83 | HTR7 (0.43) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL9379902 | 0.83 | MTNR1A (0.45) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL7111930 | 0.82 | DRD2 (0.46) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL9040773 | 0.82 | MTNR1A (0.43) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL13533358 | 0.78 | DRD2 (0.43) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL7117287 | 0.78 | L3MBTL1 (0.45) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| SCHEMBL7109070 | 0.78 | L3MBTL1 (0.45) | DRD2DRD3DRD4MTNR1AMTNR1B | |
| SCHEMBL6626738 | 0.77 | KDM4E (0.48) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL7399813 | 0.77 | PRKAB2 (0.48) | CHRM2CHRM1CHRM3DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841183-B2 | Process for producing aspartame derivatives, process for purifying aspartame derivatives, production intermediates, and process for producing production intermediates | AJINOMOTO CO., INC. (JP) | 2005-01-11 | — | — | US | disclosed |
| US-20020127320-A1 | Process for producing aspartame derivatives, process for purifying aspartame derivatives, production intermediates, and process for producing production intermediates | AJINOMOTO CO., INC. (JP) | 2002-09-12 | — | — | US | disclosed |
| EP-1227104-A1 | PROCESSES FOR PRODUCING AND PURIFYING ASPARTAME DERIVATIVES AND PROCESS FOR PRODUCING PRODUCTION INTERMEDIATES | Ajinomoto Co., Inc. (JP) | 2002-07-31 | — | — | EP | disclosed |