Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 17/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429034 | 0.82 | MEN1 (0.54) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9388133 | 0.77 | HRH1 (0.44) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9201846 | 0.76 | MEN1 (0.63) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9205131 | 0.75 | ALDH1A1 (0.81) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9429398 | 0.74 | HTR1A (0.56) | ALDH1A1KMT2AHRH1 | |
| SCHEMBL9202257 | 0.73 | MEN1 (0.59) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| Hydrochloric Acid SCHEMBL9428830 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KMT2AHRH1 | |
| SCHEMBL9870796 | 0.73 | LMNA (0.50) | MEN1ALDH1A1KMT2A | |
| SCHEMBL9430824 | 0.73 | ALDH1A1 (0.63) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9386499 | 0.72 | ALDH1A1 (0.58) | MEN1ALDH1A1KMT2AHRH1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |