Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | THPO | P40225 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22852450 | 0.89 | RAD52 (0.47) | RAD52ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL22852453 | 0.76 | RAD52 (1.00) | RAD52ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL11100764 | 0.75 | KDM4E (0.42) | ALDH1A1MAPTCYP3A4LMNAKDM4E | |
| SCHEMBL9397242 | 0.74 | RAD52 (0.43) | RAD52ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL16605573 | 0.73 | KDM4E (0.40) | ALDH1A1MAPTKDM4EALOX15TDP1 | |
| SCHEMBL24803566 | 0.70 | KDM4E (0.38) | RAD52ALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL30758546 | 0.70 | KDM4E (0.38) | RAD52ALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL26405589 | 0.70 | ALOX15 (0.47) | ALDH1A1MAPTSMN1; SMN2ALOX15TSHR | |
| SCHEMBL22852447 | 0.70 | RAD52 (0.36) | RAD52ALDH1A1MAPTKDM4EALOX15 | |
| SCHEMBL268919 | 0.70 | PARP1 (0.39) | ALDH1A1MAPTKDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284774-A | Antineoplastic, system-L specific amino acid nitrogen mustards | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECY. OF THE DEPT. OF HEALTH & HUMAN RESOURCES (US) | 1994-02-08 | — | — | US | claimed |
| US-4772632-A | REDUCED MYELOSUPPRESSION | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1988-09-20 | — | — | US | claimed |
| US-20240216529-A1 | EXTRACELLULAR VESICLES WITH TARGETING MOIETY | BIORCHESTRA CO., LTD. (KR) | 2024-07-04 | — | — | US | disclosed |
| US-20240216529-A1 | EXTRACELLULAR VESICLES WITH TARGETING MOIETY | BIORCHESTRA CO., LTD. (KR) | 2024-07-04 | — | — | US | disclosed |
| WO-2024009268-A1 | MICELLAR NANOPARTICLES AND USES THEREOF | BIORCHESTRA CO., LTD. (KR) | 2024-01-11 | — | — | WO | disclosed |
| US-11839624-B2 | Micellar nanoparticles and uses thereof | BIORCHESTRA CO., LTD. (KR) | 2023-12-12 | — | — | US | disclosed |
| US-11839624-B2 | Micellar nanoparticles and uses thereof | BIORCHESTRA CO., LTD. (KR) | 2023-12-12 | — | — | US | disclosed |
| WO-2022144811-A1 | MICELLAR NANOPARTICLES AND USES THEREOF | BIORCHESTRA CO., LTD. (KR) | 2022-07-07 | — | — | WO | disclosed |
| WO-2020261227-A1 | MICELLAR NANOPARTICLES AND USES THEREOF | BIORCHESTRA CO., LTD. (KR) | 2020-12-30 | — | — | WO | disclosed |
| US-5284774-A | Antineoplastic, system-L specific amino acid nitrogen mustards | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECY. OF THE DEPT. OF HEALTH & HUMAN RESOURCES (US) | 1994-02-08 | — | — | US | disclosed |
| US-4772632-A | REDUCED MYELOSUPPRESSION | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1988-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216529-A1 | EXTRACELLULAR VESICLES WITH TARGETING MOIETY | EXOSC5, EXOSC4, EXOSC10 | RAD52 3957/4885ALDH1A1 3325/4885MAPT 2808/4885 |
| US-11839624-B2 | Micellar nanoparticles and uses thereof | TLR9, HNRNPLL, POLRMT | RAD52 3764/4885ALDH1A1 4554/4885MAPT 1897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.