Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359013 | 0.83 | ELANE (0.39) | ELANE | |
| SCHEMBL9184350 | 0.81 | MAPT (0.44) | HDAC1 | |
| SCHEMBL9402745 | 0.79 | TDP1 (0.44) | ELANE | |
| SCHEMBL9402882 | 0.77 | MAPT (0.43) | ELANE | |
| SCHEMBL9402776 | 0.77 | KDM4E (0.47) | ELANE | |
| SCHEMBL9402700 | 0.76 | MAPT (0.50) | ELANE | |
| SCHEMBL9402620 | 0.76 | MAPT (0.46) | ELANE | |
| SCHEMBL1074876 | 0.76 | TDP1 (0.52) | HDAC8HDAC1HDAC6HDAC3 | |
| SCHEMBL9402614 | 0.76 | CYP1A2 (0.41) | HDAC1 | |
| SCHEMBL12764358 | 0.74 | TAS1R3 (0.55) | MAPK14MAPK11MAPK13MAPK12HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |