Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | ACLY | P53396 | 5/20 | 0.58 |
| ▸ | METAP2 | P50579 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.52 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.52 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417385 | 0.85 | MEN1 (0.72) | MCL1KMT2AMEN1ACLYMETAP2 | |
| SCHEMBL25734203 | 0.81 | ACLY (0.58) | KMT2AMEN1ACLYMETAP2ALDH1A1 | |
| SCHEMBL9864681 | 0.80 | METAP2 (0.58) | MCL1KMT2AMEN1ACLYMETAP2 | |
| SCHEMBL12200959 | 0.79 | CYP2C9 (0.61) | MCL1KMT2AMEN1ACLYMETAP2 | |
| SCHEMBL9402983 | 0.78 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL3554601 | 0.78 | MEN1 (0.57) | MCL1KMT2AMEN1METAP2ALDH1A1 | |
| SCHEMBL12201452 | 0.77 | ACLY (0.74) | MCL1ACLYMETAP2ALDH1A1HPGD | |
| SCHEMBL9997289 | 0.76 | PFKFB3 (0.61) | MCL1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL17331322 | 0.76 | CYP2C9 (0.60) | MCL1KMT2AMEN1METAP2ALDH1A1 | |
| SCHEMBL3982602 | 0.76 | METAP2 (0.79) | MCL1KMT2AMEN1METAP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336681-A | Elastase inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |