Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9403377 | 0.89 | PGR (0.50) | OPRM1SMN1; SMN2LMNAESR1PGR | |
| SCHEMBL14242602 | 0.85 | ACHE (0.60) | ACHE | |
| SCHEMBL607389 | 0.81 | CYP19A1 (0.52) | LMNAESR1 | |
| SCHEMBL2926301 | 0.81 | KMT2A (0.57) | SMN1; SMN2LMNAESR1ADORA3ATM | |
| SCHEMBL20533150 | 0.78 | ACHE (0.54) | OPRM1SMN1; SMN2LMNAESR1PGR | |
| SCHEMBL22448486 | 0.78 | LMNA (0.59) | OPRM1SMN1; SMN2LMNAESR1PGR | |
| SCHEMBL30748091 | 0.77 | CHRNB2 (0.45) | OPRM1SMN1; SMN2LMNAESR1PGR | |
| SCHEMBL26649920 | 0.77 | CHRNB2 (0.45) | OPRM1SMN1; SMN2LMNAESR1PGR | |
| SCHEMBL32779 | 0.77 | NPC1 (0.49) | LMNAPGRMAPTPOLBALDH1A1 | |
| SCHEMBL14374374 | 0.76 | ACHE (0.50) | OPRM1ACHEOPRD1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338740-A | Angiotensin II receptor antagonists | PFIZER INC. (US) | 1994-08-16 | — | — | US | disclosed |