Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9403350 | 0.89 | OPRM1 (0.56) | PGRESR1OPRM1SMN1; SMN2ADORA3 | |
| SCHEMBL24583699 | 0.86 | MEN1 (0.44) | PGRESR1OPRM1SMN1; SMN2ADORA3 | |
| SCHEMBL20533150 | 0.86 | ACHE (0.54) | PGRESR1OPRM1SMN1; SMN2ADORA3 | |
| SCHEMBL3069878 | 0.83 | CHRNA7 (0.49) | LMNAHSD17B10 | |
| SCHEMBL9261533 | 0.79 | ALOX15 (0.56) | PGRESR1SMN1; SMN2ADORA3AR | |
| SCHEMBL345441 | 0.78 | CHRNA7 (0.50) | — | |
| SCHEMBL3896033 | 0.76 | SMN1; SMN2 (0.55) | PGRESR1SMN1; SMN2ADORA3AR | |
| SCHEMBL9221653 | 0.76 | PGR (0.43) | PGRESR1LMNAMAPT | |
| SCHEMBL16499649 | 0.75 | CHRNB2 (0.45) | SMN1; SMN2ATMMAPTKDM4E | |
| SCHEMBL14242602 | 0.75 | ACHE (0.60) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338740-A | Angiotensin II receptor antagonists | PFIZER INC. (US) | 1994-08-16 | — | — | US | disclosed |