Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.41 |
| ▸ | CBFB | Q13951 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23868952 | 0.73 | ESR1 (0.43) | ALDH1A1TP53MEN1KMT2ATLR8 | |
| SCHEMBL27937958 | 0.69 | TLR8 (0.45) | MEN1KMT2ATLR8GAA | |
| SCHEMBL11147478 | 0.68 | CDC25B (0.65) | ALDH1A1TP53MEN1KMT2AMAPT | |
| SCHEMBL25452375 | 0.68 | ADRA2A (0.50) | ALDH1A1TP53MEN1KMT2AMAPT | |
| SCHEMBL1402424 | 0.67 | CYP1A2 (0.63) | ALDH1A1TLR8HSD17B10TSHRTDP1 | |
| SCHEMBL10654473 | 0.66 | ALDH1A1 (0.56) | ALDH1A1TP53MEN1BLMKMT2A | |
| SCHEMBL176305 | 0.65 | RXFP1 (0.54) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL9156203 | 0.64 | CASP6 (0.64) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL19680603 | 0.64 | LMNA (0.66) | ALDH1A1TP53MEN1KMT2ATLR8 | |
| SCHEMBL9388104 | 0.63 | KDM4E (0.44) | ALDH1A1TP53KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338740-A | Angiotensin II receptor antagonists | PFIZER INC. (US) | 1994-08-16 | — | — | US | disclosed |