Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.56 |
| ▸ | HRH1 | P35367 | 4/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.56 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13051501 | 0.83 | HTR2A (0.78) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL8248673 | 0.79 | HTR2A (0.79) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL11222427 | 0.79 | HTR2A (0.61) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL22018905 | 0.79 | HTR2A (0.61) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL7981739 | 0.79 | HTR2A (0.61) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL8195736 | 0.79 | HTR2A (0.61) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL6637686 | 0.79 | HTR2A (0.61) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL1799258 | 0.79 | HTR2A (0.56) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL6419291 | 0.77 | MEN1 (0.66) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL3131059 | 0.76 | ALDH1A1 (0.78) | CHRM2CHRM1CHRM3LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585314-A1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS. | NOVO NORDISK AS (DK) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020658-A1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS | NOVO NORDISK A/S (DK) | 1992-11-26 | — | — | WO | disclosed |