Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.51 |
| ▸ | HRH1 | P35367 | 4/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.51 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19852198 | 0.81 | HTR7 (0.59) | DRD3DRD2HTR7DRD4HTR1A | |
| SCHEMBL28003954 | 0.79 | ALDH1A1 (0.70) | CHRM2CHRM1CHRM3LMNAMAPT | |
| SCHEMBL9404599 | 0.79 | HTR2A (0.61) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL4920568 | 0.78 | SLC6A4 (0.65) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL13051501 | 0.78 | HTR2A (0.78) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL21245399 | 0.77 | SLC6A4 (0.59) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL3660183 | 0.76 | ALDH1A1 (0.62) | CHRM2CHRM1DRD3DRD2CHRM3 | |
| SCHEMBL4431813 | 0.75 | POLB (0.61) | CHRM2CHRM1DRD3DRD2CHRM3 | |
| SCHEMBL22018905 | 0.75 | HTR2A (0.61) | HTR2ASLC6A4SLC6A2HRH1CHRM2 | |
| SCHEMBL11222427 | 0.75 | HTR2A (0.61) | HTR2ASLC6A4SLC6A2HRH1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951796-B2 | 9-amino-acridine derivatives and their use for eliminating misfolded proteins | KORTH CARSTEN | 2011-05-31 | — | — | US | disclosed |
| US-20090209516-A1 | 9-AMINO-ACRIDINE DERIVATIVES AND METHOD OF TREATING AUTOIMMUNE DISEASES USING THE SAME | KORTH CARSTEN | 2009-08-20 | — | — | US | disclosed |
| US-20090124001-A1 | 9-AMINO-ACRIDINE DERIVATIVES AND THEIR USE FOR ELIMINATING MISFOLDED PROTEINS | HEINRICH-HEINE UNIVERSITÄT DUSSELDORF (DE) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209516-A1 | 9-AMINO-ACRIDINE DERIVATIVES AND METHOD OF TREATING AUTOIMMUNE DISEASES USING THE SAME | SSB, HSPA5, UACA | HTR2A 2033/4885SLC6A4 1748/4885SLC6A2 1866/4885 |
| US-20090124001-A1 | 9-AMINO-ACRIDINE DERIVATIVES AND THEIR USE FOR ELIMINATING MISFOLDED PROTEINS | HSPA5, ERP29, DNAJC10 | HTR2A 2234/4885SLC6A4 2239/4885SLC6A2 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.