Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326912 | 0.85 | SIGMAR1 (0.52) | SIGMAR1 | |
| SCHEMBL7364335 | 0.85 | SIGMAR1 (0.71) | SIGMAR1 | |
| SCHEMBL7321964 | 0.80 | HRH3 (0.64) | SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL27431543 | 0.79 | SIGMAR1 (0.64) | SIGMAR1HRH3 | |
| Oxalic Acid SCHEMBL7326226 | 0.79 | DRD2 (0.54) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7355256 | 0.78 | NFE2L2 (0.54) | HRH3 | |
| SCHEMBL30674540 | 0.78 | NFE2L2 (0.70) | HRH3 | |
| SCHEMBL4326032 | 0.75 | NPY1R (0.50) | SIGMAR1 | |
| SCHEMBL11447680 | 0.75 | LTA4H (0.48) | HRH3 | |
| SCHEMBL13280221 | 0.75 | KCNH2 (0.53) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580776-A1 | USE OF SIGMA RECEPTOR ANTAGONISTS TO ENHANCE THE EFFECTS OF ANTIPSYCHOTIC DRUGS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-02-02 | — | — | EP | claimed |
| WO-1992018127-A1 | USE OF SIGMA RECEPTOR ANTAGONISTS TO ENHANCE THE EFFECTS OF ANTIPSYCHOTIC DRUGS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-10-29 | — | — | WO | claimed |