Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 10/20 | 0.54 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084562 | 0.96 | HTR4 (0.49) | HTR4HTR3ADRD2HTR3EHTR3B | |
| SCHEMBL11078368 | 0.87 | HTR4 (0.39) | HTR4 | |
| SCHEMBL7381604 | 0.85 | DRD2 (0.44) | HTR4HTR3ADRD2HTR3EHTR3B | |
| SCHEMBL21055572 | 0.85 | DRD2 (0.53) | HTR4HTR3ADRD2 | |
| SCHEMBL3314494 | 0.85 | DRD2 (0.53) | HTR4HTR3ADRD2 | |
| SCHEMBL21054909 | 0.85 | DRD2 (0.53) | HTR4HTR3ADRD2 | |
| SCHEMBL7372752 | 0.85 | LMNA (0.47) | HTR4HTR3ADRD2 | |
| SCHEMBL11083119 | 0.84 | SLC6A3 (0.43) | DRD2 | |
| SCHEMBL11050072 | 0.84 | ALDH1A1 (0.58) | DRD2 | |
| SCHEMBL11049333 | 0.84 | ALDH1A1 (0.47) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282547-B1 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN | ERBAMONT INC (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0282547-A4 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN | — | 1990-11-28 | — | — | EP | disclosed |
| EP-0236646-B1 | ORTHO-ANISAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATIONS | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1990-10-10 | — | — | EP | disclosed |
| EP-0282547-A1 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN. | ADRIA LAB INC (US) | 1988-09-21 | — | — | EP | disclosed |
| WO-1988001866-A1 | METHOD FOR CONTROLLING EMESIS CAUSED BY CHEMOTHERAPEUTIC AGENTS AND ANTIEMETIC AGENTS USEFUL THEREIN | ADRIA LABORATORIES, INC. (US) | 1988-03-24 | — | — | WO | disclosed |