Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1357604 | 0.80 | SLC6A2 (0.50) | SLC6A2TAAR1LMNACYP2D6SMN1; SMN2 | |
| SCHEMBL5682273 | 0.78 | SLC6A2 (0.43) | SLC6A2TAAR1LMNACYP2D6SMN1; SMN2 | |
| SCHEMBL11211433 | 0.77 | SLC6A2 (0.46) | SLC6A2TAAR1LMNACYP2D6SMN1; SMN2 | |
| SCHEMBL4964541 | 0.76 | SLC6A2 (0.50) | SLC6A2TAAR1LMNACYP2D6SMN1; SMN2 | |
| SCHEMBL6909686 | 0.76 | SLC6A2 (0.50) | SLC6A2TAAR1LMNACYP2D6SMN1; SMN2 | |
| SCHEMBL5088767 | 0.76 | SLC6A2 (0.50) | SLC6A2TAAR1LMNACYP2D6SMN1; SMN2 | |
| Methane SCHEMBL27048839 | 0.74 | TAAR1 (0.48) | SLC6A2TAAR1LMNACYP2D6SMN1; SMN2 | |
| SCHEMBL10462120 | 0.74 | SLC6A2 (0.54) | SLC6A2TAAR1LMNACYP2D6SMN1; SMN2 | |
| SCHEMBL872871 | 0.74 | SLC6A2 (0.54) | SLC6A2TAAR1LMNACYP2D6SMN1; SMN2 | |
| SCHEMBL94458 | 0.73 | SLC6A2 (0.58) | SLC6A2TAAR1LMNACYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9263767-B2 | Electrolyte solution for electrochemical devices | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20140162143-A1 | ELECTROLYTE SOLUTION FOR ELECTROCHEMICAL DEVICES | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-06-12 | — | — | US | disclosed |
| EP-2738862-A1 | ELECTROLYTE SOLUTION FOR ELECTROCHEMICAL DEVICES | Wako Pure Chemical Industries, Ltd. (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8163938-B2 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP. (CA) | 2012-04-24 | — | — | US | disclosed |
| EP-1666459-B1 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP (CA) | 2011-10-19 | — | — | EP | disclosed |
| EP-2298735-A1 | Aminocyclohexyl ether compounds and uses thereof | Cardiome Pharma Corp. (CA) | 2011-03-23 | — | — | EP | disclosed |
| US-20110004006-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP. (CA) | 2011-01-06 | — | — | US | disclosed |
| US-7767830-B2 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP. (CA) | 2010-08-03 | — | — | US | disclosed |
| US-7345087-B2 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP. (CA) | 2008-03-18 | — | — | US | disclosed |
| US-20070254945-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP. (CA) | 2007-11-01 | — | — | US | disclosed |
| US-20070197632-A1 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070099983-A1 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP. (CA) | 2007-05-03 | — | — | US | disclosed |
| US-20060247300-A1 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP (CA) | 2006-11-02 | — | — | US | disclosed |
| EP-1666459-A2 | Aminocyclohexyl ether compounds and uses thereof | Cardiome Pharma Corp. (CA) | 2006-06-07 | — | — | EP | disclosed |
| EP-1560812-B1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP (CA) | 2006-05-10 | — | — | EP | disclosed |
| EP-1560812-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | Cardiome Pharma Corp. (CA) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004099137-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP. (CA) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004006-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | KCNH2, KCNC1, KCNH3 | SLC6A2 1012/4885TAAR1 820/4885LMNA 392/4885 |
| US-20070254945-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | KCNH2, KCNC1, KCNH3 | SLC6A2 1012/4885TAAR1 820/4885LMNA 392/4885 |
| US-20070197632-A1 | Aminocyclohexyl ether compounds and uses thereof | KCNH2, KCNC1, KCNH3 | SLC6A2 1012/4885TAAR1 820/4885LMNA 392/4885 |
| US-20070099983-A1 | Aminocyclohexyl ether compounds and uses thereof | KCNH2, KCNC1, KCNH3 | SLC6A2 1012/4885TAAR1 820/4885LMNA 392/4885 |
| US-20060247300-A1 | Aminocyclohexyl ether compounds and uses thereof | KCNH2, KCNC1, KCNH3 | SLC6A2 1012/4885TAAR1 820/4885LMNA 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.