Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408081 | 1.00 | ALDH1A1 (0.55) | ALDH1A1HTR2AHTR2CHTR2BL3MBTL1 | |
| SCHEMBL9407966 | 0.88 | HTR2A (0.55) | ALDH1A1HTR2AHTR2CHTR2BATM | |
| SCHEMBL9407965 | 0.88 | HTR2A (0.55) | ALDH1A1HTR2AHTR2CHTR2BATM | |
| Hydrochloric Acid SCHEMBL9408037 | 0.84 | LGMN (0.45) | ALDH1A1HPGDMAPTKMT2ANPC1 | |
| SCHEMBL13099111 | 0.76 | USP2 (0.41) | ALDH1A1MAPTHTTUSP2 | |
| SCHEMBL13099112 | 0.75 | DRD2 (0.44) | ALDH1A1HTR2AMAPTUSP2 | |
| SCHEMBL608528 | 0.74 | ALDH1A1 (0.76) | ALDH1A1CCR8MAPTKMT2AKDM4E | |
| SCHEMBL9408125 | 0.74 | DGAT1 (0.38) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL9408121 | 0.74 | DGAT1 (0.38) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9408126 | 0.73 | MAPT (0.41) | MAPTKMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608858-A1 | 5-Membered heterocycles as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |