Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611120 | 0.76 | AGTR1 (0.55) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8552171 | 0.76 | MAP2K1 (0.40) | KDM4EALDH1A1L3MBTL1TDP1LMNA | |
| SCHEMBL10924590 | 0.75 | ALDH1A1 (0.49) | KDM4EALDH1A1L3MBTL1TDP1LMNA | |
| SCHEMBL6606838 | 0.75 | AGTR1 (0.53) | KDM4EALDH1A1L3MBTL1TDP1LMNA | |
| SCHEMBL9409377 | 0.75 | AGTR1 (0.40) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL6608915 | 0.74 | AGTR1 (0.42) | KDM4EALDH1A1L3MBTL1TDP1LMNA | |
| SCHEMBL6606990 | 0.73 | AGTR1 (0.57) | — | |
| SCHEMBL8553595 | 0.71 | LTB4R2 (0.45) | KDM4EALDH1A1L3MBTL1TDP1LMNA | |
| SCHEMBL2730 | 0.68 | LTB4R2 (0.53) | OXTRAVPR1ALTB4R2 | |
| SCHEMBL8550700 | 0.68 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588299-A2 | 1,2,4-Oxadiazolyl- or 1,2,4-thiadiazolyl-biphenyl derivatives as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |