Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412548 | 0.96 | HPGD (0.45) | RORCIDH1ITGB3ITGA2BHDAC6 | |
| SCHEMBL9412439 | 0.90 | ITGB3 (0.56) | RORCIDH1ITGB3ITGA2BHDAC6 | |
| SCHEMBL9412623 | 0.90 | MAPT (0.46) | IDH1ITGB3ITGA2BHDAC6ROCK2 | |
| SCHEMBL9412511 | 0.86 | MAPT (0.45) | ITGB3ITGA2BROCK2ITGA2BRD4 | |
| SCHEMBL9412515 | 0.86 | JAK2 (0.47) | IDH1ITGB3ITGA2BROCK2ITGA2 | |
| SCHEMBL9412697 | 0.85 | SMN1; SMN2 (0.47) | ITGB3ITGA2BHDAC1ITGA2BRD4 | |
| SCHEMBL9412665 | 0.84 | MAPT (0.45) | IDH1ITGB3ITGA2BHDAC6ROCK2 | |
| SCHEMBL9412536 | 0.84 | ITGB3 (0.46) | IDH1ITGB3ITGA2BROCK2ITGA2 | |
| SCHEMBL9412452 | 0.84 | MAPT (0.44) | IDH1ITGB3ITGA2BHDAC6ROCK2 | |
| SCHEMBL9412477 | 0.83 | HDAC1 (0.42) | ITGB3ITGA2BHDAC1ROCK2ITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |